The Adastra lead clinical candidate, zotiraciclib, is initially being developed for the treatment of glioblastoma multiforme (GBM) and diffuse intrinsic pontine glioma (DIPG), two brain cancers characterized by Myc overexpression. Zotiraciclib is the subject of separate clinical studies in GBM, as well as an upcoming pilot study in DIPG.
The Adastra development programs are guided by world-class executives, key opinion leaders and advisors. The core management team has successfully transitioned its years of experience developing oncology drugs in large pharmaceutical companies into the entrepreneurial biotech environment. Adastra is backed by a syndicate of premier life sciences investors, including: Domain Associates, Lee’s Pharma, Morgenthaler Ventures, ProQuest Investments, and RusnanoMedInvest.